Non-Healing-Wounds include:
  • Diabetic Foot Ulcers

  • Pressure Ulcers

  • Non-Healing Surgical Wounds

  • Arterial Insufficiency Ulcers

  • Venous Leg Ulcers

  • Burns

  • Many Combat Wounds

Non-Healing wounds fail to heal in the normal timeline of 30 days because they get stuck in a chronic inflammatory state
(Phase 2 in Figure below)


Most, if not all non-healing wounds stall in the inflammatory phase of wound healing due to Microbial Biofilm Infection.

Biofilm is very difficult to treat and is not killed by normal antibiotic therapy.

1, 2


It is also very difficult for wound physicians to determine whether the wound treatment strategy for individual non-healing wounds is killing the biofilm infection.


This is because there is currently no point-of-care diagnostic that provides a quantitative measurement of biofilm infection.

Wound care physicians must determine whether wounds are healing or not by a very slow method of sensory perception including:

  • What the wound looks like

  • What the wound smells like

  • Whether a wound is sore to the touch

  • Listening to the patient history of the wound

  • A sixth sense born of experience

PeloGenix is developing a quantitative, point-of-care diagnostic of wound infection to indicate whether a wound is on a healing trajectory from one patient visit with their doctor to the next.

Schultz G, et al. Consensus guidelines for the identification and treatment of biofilms in chronic nonhealing wounds. Wound Rep Reg 2017, 25:744-757.

2 Hurlow J. Clinical investigation of biofilm in non-healing wounds by high resolution microscopy techniques. J Wound Care 2016, 25(Suppl 9): S11-S22.